Apple has recently released a security update (Security Update 2018-001) to address the Meltdown issue, for macOS 10.11.6 and macOS 10.12.6. The security update causes a system-wide crash for endpoints that have either DLP Agent 14.6 MP2 or DLP Agent 15.0 MP1.
A hot fix that fixes this problem is available from Symantec. The hot fix also addresses issues for macOS 10.13.2 endpoints with the DLP Agent installed, as described here for DLP Agents version 14.6 MP2 and here for DLP Agents version 15.0 MP1.
To obtain and apply the hot fix, follow these steps: