Your organization has Symantec Mail Security for Microsoft Exchange (SMSMSE) installed on Microsoft Exchange Server 2010. Your organization wants the best performance from the machine and you are looking for ways to exclude the email scanning directories from antivirus scanning.
Symptoms Symantec AntiVirus 10.1 (SAV 10.1) does not have automatic exclusions for Exchange 2010. These exclusions need to be set manually in order to prevent the local antivirus solution from scanning directories that may conflict with mail flow or cause issues to the integrity of the Information Store.
Automatic exclusions for Exchange 2010 were introduced in SEP 11 RU6 MP1. To take advantage of the latest enhancements and improvements, Symantec Technical Support recommends that the latest release of SEP and other software be installed on all servers.
Email scanning should be performed by your organization's email scanning application, such as Symantec Mail Security for Microsoft Exchange, while the local antivirus application should only scan non-email related folders.
Which folders to exclude 1. Microsoft's article below describes the folders that you must exclude from any local antivirus software (Symantec or otherwise) to ensure proper functionality of Exchange Server 2010.
3. The presence of email scanning tools for SEP and other antivirus software may conflict with mail flow on the server. The best practice is to install the antivirus client without the email scanning tools by performing a custom installation. These email scanning tools do not honor exclusions and have built-in SMTP activities that may interfere with normal and efficient email production.