The following error message may appear on the Domino console, in the console logs, in smspanic.txt, or within the stack dump of the PASS 2 section for the FATAL THREAD within the nsd log: PANIC: LookupHandle: handle out of range
In order to resolve this issue, please follow the steps below. Note: these resolution steps only apply to Symantec Mail Security for Domino versions 18.104.22.168 and 22.214.171.124 on 64-bit architectures.
Download the extension library "nnem.dll" attached here.
Stop the Domino server.
Create a backup copy of the existing library "nnem.dll". The file is located generally under C:\Program Files\IBM\Lotus\Domino
Replace the existing "nnem.dll" with the one you downloaded at step 1