You want to understand how Symantec ProxySG and Advanced Secure Gateway (ASG) work or interoperate with Microsoft Office 365.
With the introduction of MS-TURN and SIP protocol detection along with CRL distribution points certificate extension support required for Skype for Business operation there are no known issues with processing full SSL interception for all Office 365 applications and traffic. The only known issues are regarding authentication support for some Office 365 applications and performance considerations when processing Office 365 traffic in general. More details can be found in the Office 365 Web Guide.
See the Office 365 Web Guide for best practices, supported releases, configuration information, and known issues.
This article provides links to additional support knowledge base articles for topics or issues not currently covered in the Web Guide.
Minimum release recommendations for Office 365 traffic processing:
ProxySG 6.5: 126.96.36.199 (released on June 29, 2017) and later 6.5 releases
Note: Although Office 365 traffic processing is supported on 188.8.131.52, 184.108.40.206, 220.127.116.11, 18.104.22.168 or 22.214.171.124, they are no longer the recommended release. 126.96.36.199 and later 6.5 releases contain important additional fixes for Office 365 support. If you are experiencing issues with Office 365 traffic processing on versions 188.8.131.52, 184.108.40.206, 220.127.116.11, 18.104.22.168 or 22.214.171.124 see the Office 365 Web Guide for additional details on the issues with those releases and the fixes included in 126.96.36.199 to see if you are experiencing a known issue.
ProxySG 6.6: Upgrade to 188.8.131.52 or later 6.7 releases.
ProxySG 6.7: 184.108.40.206 (released on July 31, 2017) and later 6.7 releases.
Advanced Secure Gateway (ASG) 6.6: Upgrade to 220.127.116.11 or later 6.7 releases.
Advanced Secure Gateway (ASG) 6.7: 18.104.22.168 (released on July 31, 2017) and later 6.7 releases.